VTT has started a new 3-year project in September 2008 jointly with the Turku University Hospital and the Gothenburg University with the aim being prevention of type 1 diabetes. To achieve this goal the scientists will be using gut microbiota as a target. T1D is a major healthcare issue in Western countries.
The project is motivated by VTT's discovery of early metabolic signatures predictive of later progression to autoimmunity and type 1 diabetes. These metabolic signatures suggest the potential role of gut microbiota in early T1D pathogenesis. Therefore, in this project the aim is to discover specific microbes or lack of them associated with later progression to T1D, and to utilize that information for developing new prevention strategies. If the tests for the prevention strategies are successful the intervention can be considered for clinical stages.