Nutritech - Rethinking the Food Chain

NEW ARTICLE: Habitual dietary intake is associated with stool microbiota composition in monozygotic twins

22.4.2013 7:29


It has become evident that the diet has a dominant role on the stool microbiota and that the diet-driven changes in it occur. In the present study, habitual dietary intake, clinical data, quantitative polymerase chain reaction, and denaturing gradient gel electrophoresis (DGGE) were used to characterize the stool microbiota of Finnish monozygotic twins. The effect of habitual dietary intake in the stool microbiota was assessed through a hierarchical linear mixed model accounting for interpair and intrapair variations.

It was found that intakes of energy, monounsaturated fatty acids, n3 polyunsaturated fatty acids (PUFAs), n6 PUFAs, and soluble fiber had significant associations with the stool bacterial numbers. In addition, co-twins with identical energy intake had more similar numbers and DGGE-profile diversities of Bacteroides spp. than did the co-twins with different intake. Moreover, the co-twins who ingested the same amounts of saturated fatty acids had very similar DGGE profiles of Bacteroides spp., whereas the co-twins with similar consumption of fiber had a very low bifidobacterial DGGE-profile similarity. In conclusion, the findings confirm that the diet plays an important role in the modulation of the stool microbiota, in particular Bacteroides spp. and bifidobacteria.

Simões C, Maukonen J, Kaprio J, Rissanen A, Pietiläinen K, Saarela M. Habitual Dietary Intake Is Associated with Stool Microbiota Composition in Monozygotic Twins. J Nutr. 2013.

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