Nutritech - Rethinking the Food Chain

DISSERTATION: Association of the tenomodulin gene with obesity- and inflammation-related phenotypes

9.4.2009 15:05


Obesity is associated with chronic low-grade inflammation and dysregulations in the endocrinological functions of peripheral tissues, including adipose tissue. It predisposes the individual to chronic diseases, including cardiovascular diseases and type 2 diabetes (T2D), but also to other conditions affecting the quality of life, such as age-related macular degeneration (AMD). Many of the obesity-related conditions exhibit abnormal angiogenesis as a part of the pathophysiology.

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