Nutritech - Rethinking the Food Chain

Biochemical signature predicts progression to Alzheimer´s disease

20.2.2012 7:32

 

A study led by Research Professor Matej Oresic from VTT suggests that Alzheimer´s disease is preceded by a molecular signature indicative of hypoxia and up-regulated pentose phosphate pathway. This indicator can be analysed as a simple biochemical assay from a serum sample months or even years before the first symptoms of the disease occur. In a healthcare setting, the application of such an assay could therefore complement the neurocognitive assessment by the medical doctor and could be applied to identify the at-risk patients in need of further comprehensive follow-up.

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